October 2019 — Cytogenetics

By MCL Education • October 15, 2019

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A 61-year-old male developed flu-like symptoms with persistent cough. He had an episode of hemoptysis and presented for evaluation in the clinic. A chest x-ray showed a left lower lobe consolidation. A chest computed tomography (CT) scan revealed an 8.5 cm left lower lobe mass which was biopsied via bronchoscopy (Figure 1A). In addition to other ancillary testing, conventional chromosome analysis was performed which revealed the following modal karyotype: 44-45,Y,t(X;18)(p11.2;q11.2),add(2)(q37),-6,add(6)(q13),add(11)(q13),-13,+0-1r[cp20] (Figure 1B).

	Patrick Blackburn, Ph.D. Fellow, Laboratory Genetics and Genomics Mayo Clinic Assistant Professor of Laboratory Medicine Mayo Clinic College of Medicine and Science @SNP_Dogg
	Rhett Ketterling, M.D. Consultant, Laboratory Genetics and Genomics Mayo Clinic Professor of Laboratory Medicine and Pathology Mayo Clinic College of Medicine and Science

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This post was developed by our Education and Technical Publications Team.