A woman in her 60s presents with a mass in the left lobe of the thyroid and lymph node metastases. Upon thyroidectomy, the tumor histologically was composed almost entirely of complex papillary and micropapillary structures consisting of follicular cells with eosinophilic cytoplasm and apical nuclei with prominent nucleoli, decreased nuclear to cytoplasmic ratio, and loss of cellular cohesion.
|Matthew Woge, M.D.
Resident, Anatomic and Clinical Pathology
|Lori Erickson, M.D.
Consultant, Anatomic Pathology
Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science