Skip to Content

October 2019 — Gastrointestinal

A 64-year-old man was found to have an incidental liver mass on ultrasonography during a work-up for chronic kidney disease. He had a history of alcohol use, which he discontinued in 2011. On further evaluation, his liver function tests (ALT, AST, total bilirubin, and alkaline phosphatase) were within normal limit. Tests for hepatitis B and C viral infection were negative. CA 19-9, CEA, and alpha-fetoprotein were all within the normal reference range. On imaging, there was an indeterminate mass in the posterolateral right hepatic dome, measuring approximately 6.3 x 5.6 cm. We received a liver V and VIII segmentectomy, showing a single 5.9 x 5.5 x 4.6 cm red-yellow, friable, encapsulated mass, which was present at 0.5 cm form the inked margin.

Section of liver mass with fibrous capsule and adjacent liver parenchyma (H&E, 2x)
Liver mass with fibrous capsule (H&E, 2x)
Tumor cells associated with intra-tumoral and peri-tumoral lymphocytes (H&E, 40x)
Mucin stain
Markers of hepatic differentiation
Albumin by ISH (in-situ hybridization)
EBV by ISH

Your Score:  

Your Ranking:  

Aqsa Nasir, M.B.B.S.
Fellow, Surgical Pathology
Mayo Clinic
Saba Yasir, M.B.B.S.
Consultant, Anatomic Pathology
Mayo Clinic
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science
MCL Education

MCL Education

This post was developed by our Education and Technical Publications Team.