A 60-year-old woman presented for evaluation of hirsutism. She was found to have an elevated total testosterone level of 331 ng/dL(reference range 8-60 ng/dL) and androstenedione level of 276 ng/dL (reference range 30-200 ng/dL). Her DHEA sulfate was normal at 69.4 mcg/dL (reference range <15-157 mcg/dL) and TSH was normal at 2.5 mIU/L (reference range 0.3-4.2mIU/L). Imaging studies identified an enlarged left ovary with a small amount of free fluid, measuring 3.4 cm. There was no imaging evidence of extraovarian disease and the contralateral ovary was normal. She underwent bilateral salpingo-oophorectomy. See below for gross and microscopic images.
|Prasuna Muppa, M.B.B.S.
Resident, Anatomic and Clinical Pathology
J. Kenneth Schoolmeester, M.D.
Consultant, Anatomic Pathology
Assistant Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science