December 2019 — Bone and Soft Tissue

A 29 year old female presents with large, painless right abdominal wall mass. The mass was excised, and microscopic evaluation demonstrated an infiltrative spindle cell mesenchymal neoplasm with mild cellular atypia. Immunohistochemical stains showed the lesional cells to be positive for CD34 and S100, and negative for SOX-10, Melan A, HMB-45, cytokeratin AE1/AE3, tyrosinase, myogenin, MyoD1, KIT, ALK and STAT6.

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Photo of Sandra Gjorgova-Gjeorgjievski, M.D. Sandra Gjorgova Gjeorgjievski, M.D.
Fellow, Surgical Pathology
Mayo Clinic
@SGjorgova
Photo of Karen Fritchie, M.D. Karen Fritchie, M.D.
Consultant, Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science
@KarenFritchieMD
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