Elderly female with biopsy proven metastatic adenocarcinoma arising in the cecum. Past medical history is non-contributory. The patient underwent neoadjuvant therapy, with mixed response, prior to surgical management. Sections obtained from the right hemicolectomy specimen are shown below. Lesional cells are CDX2, synaptophysin, and chromogranin positive. Ki-67 proliferation index is >60%.
|Michael McCarthy, M.D.
Resident, Anatomic and Clinical Pathology
|Christopher (Chris) Hartley, M.D.
Senior Associate Consultant, Anatomic Pathology