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March 2020 — Gastroenterology

Elderly female with biopsy proven metastatic adenocarcinoma arising in the cecum. Past medical history is non-contributory. The patient underwent neoadjuvant therapy, with mixed response, prior to surgical management. Sections obtained from the right hemicolectomy specimen are shown below. Lesional cells are CDX2, synaptophysin, and chromogranin positive. Ki-67 proliferation index is >60%.

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Photo of Michael R. McCarthy, M.D. Michael McCarthy, M.D.
Resident, Anatomic and Clinical Pathology
Mayo Clinic
Photo of Christopher (Chris) Hartley, M.D. Christopher (Chris) Hartley, M.D.
Senior Associate Consultant, Anatomic Pathology
Mayo Clinic
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