April 2020 — Gastroenterology & Surgical

14 year old female presents with an abdominal/mesenteric based mass as resected.

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Image B

Immnohistochemical stains demonstrate strong cytokeratin AE1/AE3 (A) and trypsin (B) positivity within the tumor cells. Synaptophysin is negative while chromogranin is focally and weakly positive in the malignant population. B-catenin fails to show nuclear expression. The tumor cells are negative for SALL4, KIT, SF1, OCT4, NUT and inhibin. INI1 and BRG1 are retained.

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Photo of Stefan Brettfeld, D.O. Stefan Brettfeld, D.O.
Fellow, Surgical Pathology
Mayo Clinic
Photo of Rondell P. Graham, M.B.B.S. Rondell Graham, M.B.B.S.
Consultant, Anatomic Pathology
Mayo Clinic
Associate Professor of Laboratory Medicine and Pathology
Mayo Clinic College of Medicine and Science
@rondell_graham
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