April 2020 — Gastroenterology & Surgical
By MCL Education • April 14, 2020
14 year old female presents with an abdominal/mesenteric based mass as resected.
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Immnohistochemical stains demonstrate strong cytokeratin AE1/AE3 (A) and trypsin (B) positivity within the tumor cells. Synaptophysin is negative while chromogranin is focally and weakly positive in the malignant population. B-catenin fails to show nuclear expression. The tumor cells are negative for SALL4, KIT, SF1, OCT4, NUT and inhibin. INI1 and BRG1 are retained.
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![Photo of Stefan Brettfeld, D.O.](https://news.mayocliniclabs.com/n1/96e99366cea7b0de/uploads/2020/03/Brettfeld_Stefan_M_19JL-185x222.jpg) |
Stefan Brettfeld, D.O. Fellow, Surgical Pathology Mayo Clinic |
![Photo of Rondell P. Graham, M.B.B.S.](https://news.mayocliniclabs.com/n1/96e99366cea7b0de/uploads/2020/03/Graham_Rondell_P_19S-185x222.jpg) |
Rondell Graham, M.B.B.S. Consultant, Anatomic Pathology Mayo Clinic Associate Professor of Laboratory Medicine and Pathology Mayo Clinic College of Medicine and Science @rondell_graham |