Research

Researchers at the Mayo Clinic Center for Individualized Medicine have discovered that large chromosomal rearrangements present in mesothelioma could make it possible to understand which patients are likely respond better to immunotherapy.

This week’s Research Roundup highlights the effect of inorganic nitrite versus a placebo on exercise capacity among patients with heart failure with preserved ejection fraction.

This week’s Research Roundup highlights the association of apolipoprotein E ε4 with transactive response DNA-binding protein 43.

This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.

For patients who have been diagnosed with acute disseminated encephalomyelitis, Mayo researchers have found a direct correlation between a specific antibody, myelin oligodendrocyte glycoprotein—also known as MOG, and an increased risk of recurring attacks in these individuals.

This week’s Research Roundup highlights gastrointestinal and extra-intestinal manifestations of IgG4-related disease.

This week’s Research Roundup highlights neoantigenic potential of complex chromosomal rearrangements in mesothelioma.

Researchers at Mayo Clinic have identified three specific gene types that account for a known two- to three-fold increase in myeloma diagnoses among African-Americans. Researchers also demonstrated the ability to study race and racial admixture more accurately using DNA analysis. The findings were published today in Blood Cancer Journal.

This week’s Research Roundup highlights paraneoplastic neuronal intermediate filament autoimmunity.

This week’s Research Roundup highlights radical versus partial nephrectomy for cT1 renal cell carcinoma.

This week’s Research Roundup highlights carcinoid heart disease in patients with bronchopulmonary carcinoid.

This week’s Research Roundup highlights the limitations of platform assays to measure serum 25OHD level impact on guidelines and practice decision-making.

This week’s Research Roundup highlights the risk of MGUS in relatives of multiple myeloma cases by clinical and tumor characteristics.