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Recorded 2023, reviewed March 2026. Describes testing options for bile acid malabsorption.

The discovery of Kelch like protein 11 (KLHL11) IgG as a specific biomarker of neurological autoimmunity associated testicular germ cell tumor.

Dr. Matthew Binnicker addresses the dramatic decrease in flu cases, and the corresponding drop in serious illness and death related to influenza, seen throughout the country this year.

Dendritic cells play a crucial role in the body's immune response. Research has shown that too few of these cells in the blood may signal a defect in innate immunity. Up to this point, however, no clinical test has been available to count dendritic cells.

Patrice Brown, PA(ASCP), shares her story of growing up in Virginia and moving to Rochester, Minnesota to work at Mayo Clinic. She also shares her unique perspective of traveling internationally as COVID-19 was starting to spread.

In this month’s “Hot Topic,” Gessi Pino, a genetic counselor in the Biochemical Genetics Lab at Mayo Clinic, and Kimiyo Raymond, M.D., a clinical consultant in the laboratory and an expert in Congenital Disorders of Glycosylation (CDG), discuss glycosylation and its importance in human biology, highlight laboratory testing, and offer strategies to screen and diagnose CDGs.

William Morice II, M.D., Ph.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., look back at how the COVID-19 pandemic reshaped laboratory medicine throughout 2020.

Dr. Graham recalls how his upbringing influenced his outlook on life and discusses the power of investing in relationships.

Xinjie Xu, Ph.D., co-director of Mayo's Genetics and Genomics Laboratory, explains Mayo Clinic Laboratories' updated approach to testing for risk stratification of patients newly diagnosed with plasma cell proliferative disorders, such as multiple myeloma. Based on recently published data, the new testing algorithms focus on use of fluorescence in situ hybridization (FISH) panels, rather than chromosome studies.

In this month’s “Hot Topic,” John Mills, Ph.D., explains the central role of tissue immunofluorescence in the identification of neural antibodies and discusses the benefits of an integrated laboratory approach to the development and validation of novel antibody biomarkers.

A massive effort that involved numerous departments and experts, culminated in Mayo Clinic designing, testing and mass-manufacturing a 3D-printed mid-turbinate swab for COVID-19 testing.

Anja Roden, M.D., a medical director for Mayo Clinic's Immunohistochemistry Laboratory, joins this episode of the "Answers From the Lab" podcast. Dr. Roden and Bobbi Pritt, M.D., discuss the development and evaluation of immunohistochemistry in situ hybridization and polymerase chain reaction for detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissues.

Flu season is just now unfolding. But this time, it’s piggy-backed with a pandemic, which threatens to spike with the colder weather as people huddle indoors. Adding to this conundrum is the unsettling fact that, for both COVID-19 and the flu, the symptoms overlap.