Mayo Clinic Laboratories > Pathology

Elevating diagnosis through unparalleled expertise

Mayo Clinic has the most robust laboratory and pathology practice for cancer care in the world, offering testing that spans diagnostic, theranostic, and prognostic approaches. Integrated teams of Mayo Clinic pathologists provide expertise for every type and stage of cancer. Our consultative practice strives to provide the highest quality of diagnostic pathology, utilizing only ancillary testing that supports diagnosis in a cost-effective, expedient manner.

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Pathology Services

Biomarker and companion diagnostic testing Biomarker and companion diagnostic testing
Biomarker and companion diagnostic testing

Browse our suite of diagnostic, therapeutic and prognostic, quantitative and semi-quantitative immunohistochemical stains with interpretation.

Digital imaging Digital imaging
Digital imaging

Our digital imaging services can help providers gain clarity on complex cases. Whether used with immunohistochemistry (IHC) or in situ hybridization (ISH) stains or as part of a specialty renal pathology consultation, our digital imaging services can facilitate a clearer understanding of a patient’s condition.

Digital pathology Digital pathology
Digital pathology

Our digital pathology initiative enhances patient-specimen identification, reduces occurrences of lost or damaged slides, and improves overall patient care. Enabling faster diagnoses, workflow efficiencies, cost savings, and reproduceable results, digital pathology benefits both providers and patients.

Pathology consultation Pathology consultation
Pathology consultation

Completing more than 45,000 consultations each year, we bring unmatched experience to each engagement, providing answers on the most complicated cases. Applying best practices to each consultation, we provide expeditious, evidence-based results.

Primary ciliary dyskinesia Primary ciliary dyskinesia
Primary ciliary dyskinesia

Including both electron microscopy and genetic testing, our primary ciliary dyskinesia assays can provide diagnostic certainty for the rare, genetic disease and facilitate treatments that improve patient outcomes.

Subspecialty testing Subspecialty testing
Subspecialty testing

Offering a vast menu of pathological testing, our subspecialty testing spans the array of pathology. With more than 100 pathologists working in 19 specialized groups, our highly trained pathologists work collaboratively to provide the most comprehensive review of each case.

“DIGITAL PATHOLOGY HAS TRULY REVOLUTIONIZED THE WAY WE PRACTICE. IT HAS ALLOWED ME TO HAVE A QUICKER TURNAROUND TIME ON CONSULTS AND ENHANCED PRODUCTIVITY. AND IT GIVES ME MORE ACCURATE ANNOTATION OF DISTANCE OF THE MARGIN TO THE CANCER AND SIZE OF THE CANCER.”

Miglena Komforti, D.O.

Our difference

Integrated collaboration
Our integration with the clinical practice at Mayo Clinic provides a wealth of insights and experience to guide diagnosis and treatment decisions. Consultation cases may be directed to one pathologist who is an expert in the given area or directed more broadly to the subspecialty group. This collaboration enables information sharing on challenging cases and access to the most up-to-date scientific information and technologies.

Efficient, cost-effective answers
Our clinically driven algorithmic approach helps ensure the right test, for the right patient, at the right time. Our laboratory professionals define and employ comprehensive testing protocols, carefully considering the need for ancillary studies. This ensures high-quality laboratory testing that uses efficient, cost-effective methods and results in reduced laboratory spending.

Commitment to quality
Our testing employs quality management protocols that exceed the minimum requirements established by the Clinical and Laboratory Standards Institute. This ensures our testing processes, instruments, and operations are calibrated optimally. We also apply stringent protocols to specimen collection, storage, and transportation to help safeguard specimen integrity.

News and updates

The latest

Dr. William Morice provides insights on the evolving technologies in medicine

In a Fierce Healthcare article, Dr. William Morice highlights AI, digital pathology, and mass spectrometry as key advancements revolutionizing healthcare diagnostics and treatment.

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April 2023 – Pulmonary Case 2

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Pulmonary Pathology.

Pathways Case Studies: March 2023

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cytopathology, Gynecological Pathology, Surgical Pathology, Clinical Biochemistry, Hematopathology, and Laboratory Genetics and Genomics.

March 2023 – Breast Pathology Case 1

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Breast Pathology.

March 2023 – Breast Pathology Case 2

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Breast Pathology.

March 2023 – Cytopathology

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Cytopathology.

March 2023 – Hematopathology & Laboratory Genetics and Genomics

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case's sub-specialties are Hematopathology and Laboratory Genetics and Genomics.

Pathways Case Studies: February 2023

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for February include the following sub-specialties: Clinical Informatics, Cytogenetics, Endocrine Pathology, Hematopathology, and Laboratory Genetics and Genomics.

February 2023 – Hematopathology Case One

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Hematopathology.

February 2023 – Hematopathology Case Two

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Hematopathology.

How digital pathology is changing patient care at Mayo Clinic: Dr. Joaquin Garcia

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, sits down with Joaquin Garcia, M.D., chair of Mayo Clinic’s Division of Anatomic Pathology and digital pathology program to discuss how the advent of digital pathology is changing patient care at Mayo Clinic.

January 2023 – Pulmonary

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Pulmonary Pathology.

Pathways Case Studies: January 2023

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for January include the following sub-specialties: Bone and Soft Tissue Pathology, Gastroenterology Pathology, Neuropathology and Forensic Pathology, Pulmonary Pathology, Biochemical Genetics, Clinical Microbiology, Laboratory Genetics and Genomics

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