Case Studies

A 43-year-old female presents with seizures following weeks of progressive lower extremity numbness. Imaging reveals a contrast-enhancing parasagittal brain mass without other systemic findings. She[...]

A 71 yr old female with a history of a central nervous system lymphoma, an allogenic stem cell transplant and graft versus host disease was[...]

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for January include the following sub-specialties: bone and soft tissue, cellular therapy, laboratory genetics and genomics, and pulmonary

A 27-year-old man underwent amputation of the right fourth toe for a soft tissue mass. Kyriakos Chatzopoulos, M.D.Resident, Anatomic and Clinical PathologyMayo Clinic Andrew Folpe,[...]

Chimeric antigen receptor T cells (CAR T cells) represent an exciting new area of cellular therapy. Manufacturing autologous CAR T cells involves virally transducing a[...]

A 19 year old female with a complex phenotype suggestive of a mitochondrial disorder had mitochondrial DNA sequencing performed three times at an outside institution,[...]

This is a surgical pathology case of a 70-year-old woman with multiple bilateral relatively stable lung nodules and history of metastatic leiomyosarcoma of Mullerian origin[...]

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Biochemical Genetics, Bone and Soft Tissue, Dermatopathology, and Genitourinary.

A 12 week old boy presented with a 6 cm heterogeneous solid mass with cystic change, involving the mid/lower pole of the right kidney. Grossly,[...]

A 29 year old female presents with large, painless right abdominal wall mass. The mass was excised, and microscopic evaluation demonstrated an infiltrative spindle cell[...]

A 7-year old boy presented with growing skin lesion on the back. Chady Meroueh, M.D.Fellow, Clinical Informatics Mayo Clinic Thomas Flotte, M.D.Consultant, Anatomic PathologyMayo ClinicProfessor[...]

64 year old female with an outside diagnosis of porphyria cutanea tarda (PCT), with a new onset of abdominal pain. She had a complex constellation[...]

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for November include the following sub-specialties: Cytogenetics, Genetics, Gynecological, and Molecular Genetics.