PathWays

A 49-year-old male with prior history of severe progressive peripheral neuropathies in his extremities was diagnosed at an outside institution with chronic inflammatory demyelinating polyneuropathy. Treatments[...]

A 33-year-old man presented with a history of infertility. A blood sample was submitted to the laboratory for molecular analysis of Y chromosome microdeletions. Analysis[...]

A 32-year-old female presented to OB/GYN at 18 weeks gestation. Mutliple ultrasound anomalies were detected, including postaxial polydactyly, choroid plexus cysts, and omphalocele. Non-invasive prenatal[...]

Mayo Clinic laboratory experts share four case studies in this month's PathWays post and are challenging you to test your anatomic pathology and laboratory genetics knowledge. Review the cases, take the quizzes, and learn how the correct diagnosis was made. Good luck.

Images below are from a 60-year-old woman with an 8 cm retroperitoneal mass.   Nooshin Karamzadeh Dashti, M.D. Fellow, Surgical Pathology Mayo Clinic Taofic Mounajjed,[...]

A 43-year-old woman presented with a 1.2 cm nodule in the right middle lobe lung. She had a history of triple-negative breast neoplasm diagnosed two[...]

A 62-year-old female was diagnosed with biopsy-proven metastatic renal cell carcinoma in the head of the pancreas, status/post nephrectomy and ablation. She now presents with[...]

A 68-year-old woman underwent endometrial biopsy for post-menopausal bleeding, which showed endometrial adenocarcinoma, endometrioid type. The screening test for Lynch syndrome by IHC (dMMR-IHC) and[...]

This month’s PathWays Case Studies test your anatomic pathology, laboratory genetics, hematopathology, and clinical core laboratory knowledge. View each case and see if you can make the correct diagnosis.

​A six-year-old boy presented with fever and bone pain. He was found to have thrombocytopenia, anemia, and splenomegaly. MRI showed bone marrow abnormality. A hematologic malignancy[...]

​This is a 19-year-old female with microcytic anemia. A colonoscopy revealed a polyp in the descending colon. After the procedure, she developed fever, and a[...]

​A 36-year-old male presented to the clinic for routine warfarin monitoring. Blood was drawn for prothrombin time testing. In the lab, a medical technologist noted[...]

This week's case study reviews the molecular and biochemical genetic testing from a 34-year-old female. Can you make the diagnosis?