Mayo Clinic Laboratories > ASH 2024

Hematology testing

Propelling clinical trial and drug development solutions

Mayo Clinic Laboratories’ comprehensive test menu has been created to aid in screening, diagnosis, and treatment selection across the full spectrum of hematologic disorders. Through our clinical experience, we have developed and validated practice-based, data-driven algorithms that improve patient care, increase efficiency, and reduce costs.

Learn more Hematology, oncology, and hereditary test selection guide
Meet our experts Our experts will be available Dec. 7–9, 2024, at booth 2017

Explore Mayo Clinic Laboratories

Coagulation disorders Coagulation disorders
Coagulation disorders

Our Special Coagulation Laboratory has been at the forefront of patient-centered and value-based diagnostic laboratory testing, research, and patient management for nearly 90 years. The laboratory offers a broad repertoire of coagulation tests covering a wide spectrum of bleeding, thrombosing, and platelet disorders.

Lymphoid neoplasms Lymphoid neoplasms
Lymphoid neoplasms

To assist clinicians with lymphoma diagnosis, Mayo Clinic has a highly experienced, nine-member hematopathology section focusing on lymphoma diagnosis, which diagnoses more than 3,000 lymphoma cases per year.

MayoComplete next-generation sequencing MayoComplete next-generation sequencing
MayoComplete next-generation sequencing

Our menu of MayoComplete next-generation sequencing assays includes targeted testing for a growing list of hematologic cancers. Utilizing next-generation sequencing, our MayoComplete testing ensures each patient receives personalized answers to guide their care.

Myeloid neoplasms Myeloid neoplasms
Myeloid neoplasms

Our leukemia test menu includes flow cytometry, chromosome, FISH, and molecular testing. We provide accurate results and expert interpretation from a highly focused team of laboratory specialists.

Plasma cell neoplasms Plasma cell neoplasms
Plasma cell neoplasms

Our algorithmic approach ensures that the right tests are ordered at the right time, and that healthcare providers get clinically actionable answers for their patients faster.

Red blood cell disorders Red blood cell disorders
Red Blood Cell Disorders

Our Metabolic Hematology Laboratory is dedicated to providing accurate diagnoses and clinical interpretations for patients. For hematologists whose patients require only a single test, many components of our specialized can be ordered individually.

Printable documents

Download Bleeding, thrombosing, and platelet disorders
Download Myeloproliferative neoplasms
Download Monoclonal protein identification
Download Hematologic myeloid neoplasms

Highlights

A novel testing approach for newly identified VEXAS syndrome

VEXAS syndrome is a severe autoinflammatory disease that results in a spectrum of rheumatologic and hematologic conditions. The underlying cause of newly identified VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome — somatic mutations in the UBA1 gene of blood cells — was discovered at the National Institutes of Health (NIH) in 2020. Within six months, Mayo Clinic Laboratories was able to add a UBA1 test to the MayoComplete panel, as the team simultaneously worked on a single gene assay to allow doctors to test specifically for UBA1 mutations to screen patients for VEXAS syndrome. The team opted for a droplet digital PCR test — a novel and highly accurate approach to testing for UBA1 gene mutations.

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Applying MASS-FIX to Urine Samples

In this month's "Hot Topic," David Murray, M.D., Ph.D., reviews the role of urine testing for monoclonal gammopathies and discusses Mayo Clinic’s use of MASS-FIX to replace traditional immunofixation testing.

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