Mayo Clinic Laboratories > Hematology > Lymphoid neoplasms

Lymphoid neoplasms

Expert interpretation of chromosome abnormalities

Lymphomas are among the most complex diseases to recognize and diagnose because they are pathologically complex, with features that overlap with reactive/inflammatory conditions and other nonhematologic malignancies.

30

There are currently over 30 identified subtypes of T-cell neoplasms, which can make diagnosis difficult

12%

T-cell malignancies account for approximately 12% of all non-Hodgkin’s lymphomas

7th

Non-Hodgkin’s lymphoma is the seventh most common type of cancer in the U.S.

3,000

To assist clinicians with lymphoma diagnosis, Mayo Clinic has a highly experienced, nine-member hematopathology section focusing on lymphoma diagnosis, which diagnoses more than 3,000 lymphoma cases per year.

B-cell lymphoma B-cell lymphoma
B-cell lymphoma

Our B-cell lymphoma testing includes next-generation sequencing and FISH testing to identify genetic abnormalities associated with B-cell lymphoma subtypes.

B-cell and T-cell acute lymphoblastic leukemia B-cell and T-cell acute lymphoblastic leukemia
B-cell and T-cell acute lymphoblastic leukemia

Our fluorescence in situ hybridization (FISH) testing is designed to simplify the ordering process by providing diagnostic panels that include all appropriate genes.

Chronic lymphocytic leukemia Chronic lymphocytic leukemia
Chronic lymphocytic leukemia

Our approach to chronic lymphocytic leukemia testing meets all testing recommendations as well as comprehensive fluorescence in situ hybridization (FISH) panels, which detect for genetic biomarkers associated with disease severity, progression, and treatment response.

Eosinophilia Eosinophilia
Eosinophilia

Our suite of fluorescence in situ hybridization tests is designed to identify malignancies in select genes associated with eosinophilia.

Histiocytic neoplasms Histiocytic neoplasms
Histiocytic neoplasms

Our next-generation sequencing panel for histiocytic neoplasms was carefully curated to include select genes with high clinical value to characterize the disease and provide insight into the differential diagnosis of these rare tumors and therapeutic options.

T-cell lymphoma T-cell lymphoma
T-cell lymphoma

We offer next-generation sequencing and comprehensive fluorescence in situ hybridization (FISH) panels, as well as extensive immunohistochemistry (IHC) offerings, to diagnose and monitor T-cell lymphoma.

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Specialized testing helps reverse effects of stiff-person syndrome: James Kypuros

One summer morning, James Kypuros awoke to find his toes stiffened like claws. Then he started having falls, which culminated in losing his ability to walk or even sit up without help. Diagnosed with stiff-person syndrome, James wouldn’t find hope or relief until he was treated for glycine receptor antibody syndrome following specialized testing by Mayo Clinic.

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Resources
View video Paul Kurtin, M.D., consultant in Hematopathology, provides an overview of the lymphoma consultation services available through Mayo Clinic Laboratories.
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