Pathways – Clinical Pathology

A 60-year-old man presented with a slow-growing non-painful 4.5 cm mass of the left parotid gland and underwent surgical excision. Below is an hematoxylin and[...]

By MCL Education • January 8, 2019

A 52-year-old male underwent whole-exome sequencing (WES) for amyotrophic lateral sclerosis (ALS). While no germline alterations relevant to his ALS were detected, multiple de novo[...]

By MCL Education • January 8, 2019

Mayo Clinic laboratory experts share three case studies in this month’s “PathWays” post and are challenging you to test your Clinical Pathology, Molecular Diagnostic, Hematopathology, and Dermatology pathology knowledge. Review the cases, take the quizzes, and learn how the correct diagnoses were made.

By Mayo Clinic Laboratories • November 6, 2018

A 59-year-old man with a history of HIV presented with a 6 cm mass involving the left palatine tonsil. Biopsy of the mass showed the[...]

By MCL Education • November 6, 2018

A child was born with features consistent with Down syndrome. Karyotype results were 46,XY,der(21;21)(q10;q10),+21, supporting the clinical diagnosis. Parental chromosomal analysis was completed as a[...]

By MCL Education • November 6, 2018

A 13-month-old female infant was referred for delayed milestones, atrial septal defect, low-set ears, mild hypertelorism, and iridal coloboma. Chromosome analysis was performed, which showed[...]

By MCL Education • November 6, 2018

Mayo Clinic laboratory experts share four case studies in this month’s “PathWays” post and are challenging you to test your blood education, neuropathology, breast pathology, and clinical pathology knowledge. Review the cases, take the quizzes, and learn how the correct diagnoses were made.

By Erika Fetterman • October 9, 2018

A 52-year-old female presented to the emergency department with chest discomfort. Cardiac troponin I (TnI), measured using a goat antibody-based sandwich immunoassay (ADVIA Centaur, Siemens[...]

By MCL Education • October 9, 2018

Mayo Clinic laboratory experts share four case studies in this month’s PathWays post and are challenging you to test your anatomic pathology, infectious disease pathology, laboratory genetics, and gastrointestinal pathology knowledge. Review the cases, take the quizzes, and learn how the correct diagnoses were made.

By Erika Fetterman • August 7, 2018

A 25-year-old female presented with extreme malnourishment (BMI=9). Her nutrition has been suffering due to severe gastroparesis along with cyclic vomiting and food intolerance. Her[...]

By MCL Education • August 7, 2018

Mayo Clinic laboratory experts share four case studies in this month’s PathWays post and are challenging you to test your blood, clinical pathology, hematopathology, and anatomic pathology knowledge. Review the cases, take the quizzes, and learn how the correct diagnoses were made.

By Erika Fetterman • July 10, 2018

A 57-year-old female presented with easy bruising, hirsutism, and weight loss. Morning serum cortisol was 54.1 mcg/dL (reference interval (RI): 7-25 mcg/dL) with an adrenocorticotropic[...]

By MCL Education • July 10, 2018

Here, we report a case of a 56-year-old African-American female with a reported history of “alpha thal trait” found to have severe reticulocytopenic microcytic anemia[...]

By MCL Education • July 10, 2018